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Interestingly, growing evidence suggests that GLP-1RAs reduce systemic inflammation beyond local antiinflammatory effects in atherosclerotic plaques

They also appear to interact with the brains reward system, which may help reduce cravings for substances like alcohol, nicotine, and opioids

Obesity (Silver Spring) 2013;21(2):218228

The report, New Weight Loss Drugs: GLP-1 Agonist Use and Side Effects in the United States, is available at www.rand.org

Due to newfound popularity of GLP-1 agonists as a quick weight-loss solution, some have found their medications in short supply or more expensive, and in some cases, both
