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Rare but serious side effects include pancreatitis and kidney or gallbladder problems

Preclinical studies have demonstrated that GLP-1R agonists, such as exendin 4 (Ex4) and liraglutide, attenuate drug-induced dopamine release in the NAc, a key region involved in reward processing

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Weight Loss Drug Comparison: Efficacy, Muscle Loss, and Market Stage Towards a Dual-Action Approach: Fat Loss and Muscle Preservation Recognizing the need for a more balanced approach to weight management, pharmaceutical innovators are now focusing on therapies that not only promote fat loss but also preserve or enhance muscle mass (Rodgers and Christopher 2022)