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These are typically most noticeable in the first few weeks or right after a dose change, and can include nausea, diarrhea, constipation, fatigue, and abdominal pain

Frequently Asked Questions Can I eat sugar while taking semaglutide

According to studies published in Diabetologia, sitagliptin has a neutral effect on body weight making it suitable for patients who dont need weight reduction but want effective blood sugar control without weight gain

This is probably why some people notice improved bloating and appetite regulation before they notice anything on the scale

For example, if you are on 15 mg weekly, your provider might reduce to 10 mg for 4-6 weeks, then to 7.5 mg, and finally to 5 mg before complete discontinuation