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The Harmony Outcomes Trial, conducted in 2018, investigated the use of 3050 mg albiglutide once-weekly subcutaneous injection in 9463 patients with T2DM for a median of 1.5 years

Among the rare ocular side effects of GLP-1RAs is non-arteritic anterior ischemic optic neuropathy (NAION), which can cause permanent loss of vision

Most surgical guidelines now recommend stopping these medications at least one to two weeks before elective surgery

Moreover, the once-weekly dosing option improves patient compliance compared to daily injections or multiple daily oral medications, marking a significant advancement in diabetes treatment

In a statement, Scott Brunner, CEO of the Alliance for Pharmacy Compounding, questioned whether the FDA's resolution of the shortage had taken into account demand for the compounded drug and "the number of patients wholl need to be transitioned from a compounded version to a FDA-approved version. "Thats likely hundreds of thousands of patients," Brunner said