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The primary outcome of this study is the incidence of osteoporosis

As the field of weight loss treatments innovates, next-generation medications emerge with promising potential

The MASH mouse and hamster work published by Briand and colleagues in 2026 showed dose-dependent reductions in body weight, hepatic steatosis, and liver enzymes that exceeded what dual agonists produced in the same models (Briand et al., Obesity, 2026)

doi: 10.1007/s40261-019-00826-0 6 ElashoffMMatveyenkoAVGierBElashoffRButlerPC

Simultaneously, they suppress glucagon release , a hormone that raises blood glucose
