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GLP-1 receptor agonists like semaglutide have shown protective effects on kidney function in multiple clinical trials, particularly for people with type 2 diabetes

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However, current methods for quantifying MF in mouse models struggle to accurately capture its heterogeneous regional distribution, creating a significant barrier to reliably assessing the efficacy of therapeutics

GLP-1 based therapies led to statistically significant reductions in the serum levels of brain natriuretic peptide (40.16 [51.50, 28.81]
