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For many patients, this represents the first time they've experienced meaningful, sustained fat loss after years of effort with conventional approaches

When Wegovy is used alongside insulin or sulphonylureas, dose adjustments of these medications may be necessary to reduce the risk of hypoglycaemia, which in severe cases can precipitate seizures

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The research findings require validation through longitudinal studies, since GLP-1RAs might modify immune pathways in ways that could intensify inflammation for some people [51]

We estimated odds ratios of the outcome with weighted, pooled logistic regression where all follow-up intervals were included.15 In these analyses, the odds ratio for drug use can be interpreted as a hazard ratio because it is estimated over discrete follow-up intervals