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In the Phase 2 retatrutide trial, some groups used a lower starting dose (2 mg vs 4 mg) and the study notes side effects were "partially mitigated" with a lower starting dose
Diabetes Obes Metab 2015
However, it has shown remarkable efficacy in promoting weight loss
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This risk was notably higher among unvaccinated individuals, suggesting that herpes zoster vaccination may help mitigate this elevated risk
