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It is released primarily in response to food intake and controls the secretion of insulin in function of the glucose level

Acknowledgments This study was supported by a grant from the National Leading Research Laboratory (NRF-2015R1A2A1A05001832) and a grant from the Basic Science Research Program (NRF-2015M3A9E2030125) through the National Research Foundation of Korea (NRF), funded by the Ministry of Science, ICT, & Future Planning, Korean Government

The mechanism whereby metformin increases gut glucose uptake and utilisation remains unclear [3640]
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