glp-1 agonists and sglt2 inhibitors Diabetic Agents, From Metformin to GLP1 Receptor Agonists: JACC Focus Seminar Cardiovascular benefits of SGLT2 inhibitors

Monitoring and Follow-Up Care Regular medical supervision is essential when using GLP-1 medications, regardless of where you purchase them

Weight regain after bariatric surgery: scope of the problem, causes, prevention, and treatment

The new biology and pharmacology of glucagon

10 or 15 mg once weekly) vs Reduce to tirzepatide 5 mg once weekly vs Placebo for 52 weeks (randomized 3:3:2 at week 60) Primary outcome: Percent change in bodyweight from baseline to week 112 Results: Primary outcome (percent change in bodyweight at week 112): Tirzepatide MTD -21.9%, Tirzepatide 5 mg -16.6%, Placebo -9.9% (estimated treatment difference vs placebo -12.0% for MTD and -6.6% for 5 mg

GLP-1R is a core member of the G protein-coupled receptor family and is widely distributed on the surface of many human cells (Zheng et al., 2024)