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Paulus WJ, Tschpe C (2013) A novel paradigm for heart failure with preserved ejection fraction: comorbidities drive myocardial dysfunction and remodeling through coronary microvascular endothelial inflammation

To solve this, Novo uses SNAC (sodium N-[8-(2-hydroxybenzoyl) amino] caprylate), a carrier molecule that temporarily buffers local stomach pH to deactivate pepsin (the enzyme that eats protein) and permeabilizes the gastric lining

DOI: 10.1097/01.NPR.0000000000000430,

As Healio previously reported, the FDA removed tirzepatide (Mounjaro/Zepbound, Eli Lilly) and semaglutide (Ozempic/Wegovy, Novo Nordisk) from its drug shortage list in 2024 and 2025, respectively, and now prohibits both 503A compounding pharmacies and 503B outsourcing facilities from distributing compounded versions of the drug