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Research from the SURMOUNT and STEP trials showed that up to 40 percent of the weight lost on GLP-1 medications can come from lean mass (muscle), not fat

Also, as an anabolic hormone, insulin promotes fat storage, and chronic hyperinsulinemia, commonly observed in T2DM, further stimulates lipogenesis while suppressing lipolysis, thereby counteracting BW reduction

Cryo-electron microscopy structure of the glucagon receptor with a dual-agonist peptide

When food enters the digestive system, GLP-1 is released into the bloodstream, where it exerts multiple physiological effects that help maintain normal blood sugar levels

Slowing down this process makes us feel fuller for longer, leading to lower calorie intake