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Results are expected to take two to three years

[ 14 C]-Metformin uptake was 13 times higher in OCT3-BT20 cells than in BT-20 cells, and associated with increased AMPK phosphorylation and decreased pS6K phosphorylation in OCT3-BT20 cells and these results were substantiated in mice with OCT3 overexpressing tumors (241)

GLP-1 receptors are abundant in the pancreas, but are also found throughout the intestine, lung, kidney, heart, blood vessels, lymphocytes, and the peripheral and central nervous system (Figure 1)

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