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However, because large amounts of fat can worsen nausea or acid reflux in some people taking GLP-1 medications, many people find it more comfortable to include smaller portions throughout the day, such as a drizzle of olive oil on vegetables, a tablespoon of almond butter in a smoothie, a quarter of an avocado with lunch, rather than eating one high-fat meal

Keep reading to learn more, explore the FAQ section below, and visit the Quarterly Drug Pipeline for deeper insights into anticipated therapies in development

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For the efficacy estimand, the LSM change in HbA1c from baseline at week 52 as the primary endpoint was 2.24%, 2.43%, and 2.58% with tirzepatide 5, 10, and 15 mg, respectively, versus 1.44% with insulin glargine

The design of the linker can influence the conformation and stability of Peptibody, so careful selection is necessary to ensure Peptibody performance