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These metabolites interact with gut receptors and can stimulate Lcells to secrete GLP1

10.1056/NEJMoa1901118 [DOI] [PubMed] [Google Scholar] 60.Boyle JG, Livingstone R, Petrie JR

We do have to be careful about excess body weight loss, which we know sarcopenia, bone health, and so forth but we really haven't seen any other signals to date, and we're going to continue and look for those

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