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Description
Tirzepatide's pharmacokinetic profile supports weekly dosing with a half-life of approximately five days

Patients who reduced the frequency of GLP-1 dosing (from weekly to every other week) were able to maintain their weight loss and metabolic syndrome gains, as reported in this case series

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Significance statement ![Figure][1] ### Competing Interest Statement The authors have declared no competing interest

Doing so exceeds the traditional scope of pharmacy compounding and violates federal law
