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We also discuss combination therapies and strategies to mitigate muscle mass loss during treatment and calls for targeted research, improved clinical education, and policy reforms to optimize the translational potential of GLP-1R agonists in both individualized care and population health

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Januvia is typically used alongside diet and exercise and may be combined with other diabetes medications when needed

Although glucagon-like peptide-1 receptor agonists (GLP-1 RAs) are highly effective for body weight reduction, there remains a critical unmet need for complementary strategies that drive selective fat loss and sustain long-term weight reduction

GLP-1 semaglutide shows improved liver scarring in advanced MASH, early cirrhosis, offering a potential new treatment option in a large global trial study.