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Symptoms of Stomach Paralysis (Gastroparesis): Although unusual, GLP-1 medications can in rare cases lead to gastroparesis

Oncoimmunology 7 , e1382790 (2018)

Ozempic Heartburn May Be a Sign of a Serious Condition Problem-first: persistent or severe reflux can flag deeper problems, such as delayed gastric emptying that becomes disabling, biliary issues, or pancreatic inflammation

Evolutionarily, we were designed to eat as much and as fast as we can, because there was no way to preserve food. Extra calories are stored as fat, but as soon as you start losing weight, your body starts thinking somethings wrong, Suri explains, which, hormonally, makes it harder to lose weight. The body responds by increasing appetite and slowing metabolism, and the hormones that regulate feelings of hunger kick into high gear, to drive your body weight back to the set-point range. GLP-1s and GIPs help override those hunger signals while improving the insulin receptivity that allows your body to burn fat

Do not use Semaglutide after the expiration date or beyond use date (BUD) printed on the packaging or product label