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Moreover, bone microarchitecture/strength changes assessed by high-resolution peripheral quantitative computed tomography (HR-pQCT) are lacking

The dose is then gradually increased for each following week, as follows: week two: 1.2 mg per day week three: 1.8 mg per day week four: 2.4 mg per day weeks five and beyond: 3 mg per day If you have bothersome side effects after a dose increase, talk with your doctor

Most practicing surgeons would tell you that tracks with what theyre seeing

This is not a small error

however, direct evidence for improvements in hard endpoints (particularly live birth) remains limited and should be communicated as such (198, 199)