discontinue sulfonylurea when starting glp-1 receptor agonist GLP1-RA and SGLT2-i: Implementation and Insulin Deescalation Strategies | Cardiovascular Drugs and Therapy What's next after metformin for

Butler AE, Janson J, Bonner-Weir S, Ritzel R, Rizza RA, Butler PC

However, the degree of HbA1c lowering desired must be taken into account, and the relatively modest glycemic effects at lower starting HbA1c, as well as their cost compared to other agents may temper ones enthusiasm for prescribing this class of therapy

If you experience severe abdominal pain, jaundice, or difficulty passing gas while on these medications, seek immediate medical attention, as these symptoms could indicate serious issues like pancreatitis or gallbladder complications

doi:10.1111/j.1476-5381.2012.01971.x 11

Safer Alternatives for Weight Loss & Mental Wellness If weight management is impacting your mental health, alternatives may include: Structured nutritional counseling CBT or DBT for anxiety or depression causing emotional eating Mindfulness practices for stress reduction Treating underlying depression or trauma that contributes to weight changes Exercise & movement Final Thoughts DIY GLP-1 drugs from the gray market may seem like a quick fix, but they carry serious risks that can harm both body and mind