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Several factors increase the likelihood of developing telogen effluvium while on a GLP-1 medication: 1

While the recent phase 3 trial for orforglipron was specifically for type 2 diabetes and not weight loss, the study found that patients who took the drug lost considerable weight

Exendin-4, a Glucagon-like Peptide-1 Receptor Agonist, Reduces Intimal Thickening after Vascular Injury

Effect of weekly subcutaneous semaglutide vs daily liraglutide on body weight in adults with overweight or obesity without diabetes
