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Constipation is a common side effect of GLP-1 medications like semaglutide and tirzepatide

These include diarrhea, nausea, and vomiting, especially when the initiation or titration occurs too rapidly

Host: Derek Thompson Guest: David Ricks Producer: Devon Baroldi More Plain English Episodes on GLP-1s

Metabolic changes associated with weight loss can also contribute

JAMA 2025, 333, 113114
