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Non-coding variants are indicated with + symbols

A phase 3b, randomized, multicenter, controlled study of mirikizumab and placebo or mirikizumab concomitantly administered with tirzepatide in adult participants with moderately to severely active ulcerative colitis and obesity or overweight

Telogen effluvium tends to resolve once the underlying stressor has been addressed

Together, these data demonstrate that RF-409 effectively activates IR in cultured cells and recapitulates key metabolic actions of insulin in glucose and lipid metabolism

Selective serotonin reuptake inhibitors (SSRIs), particularly fluoxetine at higher doses, have shown modest efficacy in reducing binge frequency, though they are not specifically licensed for this indication