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Additionally, there was a significantly lower risk of CRC in overweight and obese patients when treated with GLP-1RAs as compared with all antidiabetics examined in this study

Safety and preliminary efficacy of intranasal insulin for cognitive impairment in Parkinson disease and multiple system atrophy: A double-blinded placebo-controlled pilot study
Obesity (Silver Spring) 2009;17(12):212733

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Its receptors are also found in fat, bone, heart, brain, and adrenal tissue, where it helps influence energy balance and metabolism, making it a key partner to GLP-1 in supporting weight management
