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Metabolic improvements often begin within weeks, before significant weight loss occurs

Other GLP-1 tablets, such as Rybelsus, have been available for type 2 diabetes in the UK for a while, but were not licensed for weight loss

Hall and other experts have concluded that the amount of muscle lost is not clinically relevant for the vast majority of people, especially when weighed against the massive cardiovascular benefits of losing harmful visceral fat

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Contactin-associated protein-like 2 ( CNTNAP2 ) mutations impair the essential -secretase cleavages, leading to autism-like phenotypes