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Yes, you should discontinue Tradjenta (linagliptin) when starting a GLP-1 receptor agonist as they have overlapping mechanisms of action, and continuing both...

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While their side effect profile is often manageable, they can lead to serious complications

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These systemic metabolic changes are likely to contribute to dysregulation of cerebrospinal fluid dynamics, primarily hypersecretion but with a possible additional effect of reduced clearance resulting in the core feature of raised intracranial pressure.

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GLP-1 receptor agonists emerged from diabetes research and now represent a major advancement in weight management

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