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GIP receptor activation enhances fat oxidation, improves lipid metabolism, and appears to have direct effects on adipose tissue distribution

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The risk of a serious underlying cause increases with age, family history of colorectal cancer, or the presence of other symptoms such as weight loss or anemia

Int J Mol Sci 23:398 Aksu I, Baykara B, Ozbal S, Cetin F, Sisman AR, Dayi A, Gencoglu C, Tas A, Byk E, Gonenc-Arda S, Uysal N (2012) Maternal treadmill exercise during pregnancy decreases anxiety and increases rat pups prefrontal cortex VEGF and BDNF levels in early and late periods of life