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This finding was significant enough that the tirzepatide drug label now advises patients using oral hormonal contraceptives to switch to or add a non-oral contraceptive method when initiating tirzepatide and after each dose escalation

While GLP-1 drugs were first approved to treat type 2 diabetes in 2005, the class of medications have become more popular in recent years, especially as Wegovy (semaglutide) was approved for weight loss in June 2021

Anaerobe (2018) 54:1213

Stay hydrated: Many side effects worsen with dehydration

And these drugs have been used for diabetes for over a decade so safety is well understood
