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56 Taken together, it is clear that GIPR signalling affects bone turnover, but the overall significance of these effects need to be fully determined

For this reason, many patients and providers view GLP-1 medications as long-term or indefinite treatments rather than short-term interventions, particularly for patients with significant weight to lose or metabolic conditions

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This external constraint explains the lower NP levels and echocardiographic filling pressure estimates observed in obese HFpEF patients than in nonobese individuals

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