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If its discolored or contains particles, do not use it

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Operative versus Nonoperative Management for Appendicitis, New England Journal of Medicine, 395 , 1, (86-89), (2026)./doi/full/10.1056/NEJMclde2600182 Cost-effectiveness and superior clinical outcomes of appendectomy are evidenced within 6 months of the index admission for uncomplicated appendicitis compared to nonoperative management, Surgery, 194 , (110150), (2026)

For precise out-of-pocket estimates, patients should compare available program tiers, consult with prescribing clinicians, and investigate FSA/HSA applicability