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GLP-1 medications like semaglutide (Wegovy) are in demand for their efficacy in weight loss

Regarding the central mechanism of feeding regulation, proopiomelanocortin (POMC) neurons in the arcuate nucleus (ARC) of the hypothalamus are key anorexigenic neurons

These changes typically reflect positive therapeutic effects rather than direct medication side effects

doi:10.1038/nature22378
