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The GLP-1R agonist liraglutide limits hepatic lipotoxicity and inflammatory response in mice fed a methionine-choline deficient diet

This not only indicates that oral semaglutide has similar efficacy in the treatment of obesity compared to the injectable form but also that its oral route of administration may help overcome psychological barriers to injection therapy for some patients, thus improving compliance and acceptance

95% CI [0.681.13])

Interestingly, this is the same region of the brain responsible for the food intake reduction effects of estrogen

This eliminates math errors that are especially consequential at the starting dose level