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This reorganization pulls water away from the peptide surface, destabilizing the hydration shell
Explore the research: spkl.io/6013ACDgN Presented today at #ECO2026 The SURMOUNT-MAINTAIN trial found that continuing tirzepatide at the maximum tolerated dose maintained bodyweight reduction and health-related benefits in adults with obesity
Several clinical conditions warrant caution

While these mechanisms contribute to its therapeutic benefits, they also explain why gastrointestinal side effects are among the most commonly reported adverse reactions

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