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In general, large hypertrophic adipocytes are considered metabolically unfavorable and are associated with various pathophysiological conditions

Borlaug BA, Zile MR, Kramer CM, et al

Key end points included: hospitalisation, heart failure (ICD-10-CM-I50), myocardial infarction (ICD-10-CM-I21), stroke and transient ischaemic attack (ICD-10-CM-I63, G45), development of diabetic microvascular complications (ICD-10-CM-E10.210.4) and all-cause mortality analysed 3 months to 5 years post drug initiation

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