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This information should be clearly documented in medical records to ensure all healthcare professionals involved in the patient's care are aware

In a 2024 cryo-EM structure paper published in Cell Discovery, researchers resolved retatrutide bound to each of the three receptors and showed the same peptide adopting a continuous alpha-helical conformation across all three, with receptor-specific contacts in the extracellular loops that tune potency at each target

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If the regained weight is disproportionately fat, individuals may ultimately be worse off than before in their fat-to-lean mass ratio, which may have adverse consequences for their health. The researchers say there are several limitations to their study