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Constipation affects up to 25% of people starting GLP-1 therapy like semaglutide

Weight loss on GLP-1 medications typically begins within 412 weeks, with most users seeing 515% body weight reduction by 6 months

The popular weight-loss drug can now be used to reduce the risk of stroke, heart attacks and other serious cardiovascular problems in patients who are overweight or who have obesity, the FDA said.

Key points: - Weight loss in Parkinson's disease was associated w/ greater cognitive decline, whereas weight gain was associated w/ slower motor progression in previous longitudinal studies

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