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Using pricing information from other medicines that recently went off patent, researchers in Britain, South Africa, and New Zealand calculated the potential generic manufacturing price for semaglutide

In reality, up to 70% of patients stop GLP-1 treatment within a year most often due to: High cost (GLP-1s can cost $1,000+ per month without insurance) Loss of insurance coverage for weight loss treatment Side effects such as nausea, diarrhea, constipation, or fatigue A Misconceptions some patients stop once they lose initial weight, believing they no longer need the medication 2

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Physical activity: Patients who exercise, particularly with resistance training, typically lose more weight and maintain better body composition
