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189,190 In addition, the mitochondrial PGC-1 signaling pathway is also the mechanism of GLP-1 RA to protect neurons from tau hyperphosphorylation, indicating that mitochondrial dysregulation has crosstalk with tau pathology
Despite exenatide showing a higher reported number of reactions compared to liraglutide (2539:1981), the associations with acute pancreatitis events were weaker, which was also observed in cases of pancreatic cancer (Cao et al., 2023)
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Tracy Norfleet, MD, FACP, notes: "Injection site reactions may get worse over the first 24 hours, and should improve thereafter
PMID:10098504
