glp-1 weight loss timeline of critical milestones in the development and use of What are GLP-1s? | Mendinground
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Other trials also reported a reduction in body weight, HbA1c, and FPG in patients receiving combination therapy with SGLT-2i plus GLP-1RA [9, 23, 46]

In 2021, the results of a meta-analysis that included 7 RCT studies showed that GLP-RA uses resulted in a decreased risk of respiratory disease [43]

There have been postmarketing reports of severe and disabling arthralgia in patients taking DPP-4 inhibitors

However, they are serious and should be factored into the riskbenefit discussion when considering GLP-1 therapy with a doctor

doi: 10.1016/j.jad.2018.04.042
