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By Connor Iapoce The FDA accepted the NDA for oral semaglutide 25 mg, a potentially revolutionary daily treatment for weight management and cardiovascular risk reduction
Early clinical results suggest the treatment is safe and well tolerated.
Independent editorial review not affiliated with the brand

The Protein-Muscle Problem Research shows that up to 20 to 25 percent of weight lost on GLP-1 medications can come from muscle rather than fat

Mendelsohn lays out why Vivani shifted from a broad platform story to focusing 90% of the company on a GLP-1 drugdevice product, how theyre using the 505(b)(2) pathway to shorten development by leveraging existing semaglutide data, and why the ability to stop treatment by removing the implant addresses a limitation of long-acting injectables
