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Description
Lab work baseline metabolic panels and periodic re-checks are clinically appropriate on GLP-1s and not always covered
Nature 494:185194
Women in their 50s
The analysis of 4887 participants treated with tirzepatide and 2,328 participants in the control groups identified 142 participants who developed at least one MACE-4p (inclusive of cardiovascular mortality, myocardial infarction, stroke, and hospitalization for unstable angina) and confirmed the cardiovascular safety with an hazard ratio (HR) of 0.80 (95% CI 0.571.11) for the comparison between tirzepatide and controls
Comparative metabolomics analysis revealed that GLP-1RAs significantly altered both faecal and colonic metabolic profiles
