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Until more evidence is available, in this individualized risk and benefit decision-making, one should not assume that this risk is specific to semaglutide. Taken in total, the summary noted that currently available evidence suggests a possible association between semaglutide and NAION

Patients diagnosed with diabetes may be eligible for insurance coverage

Patients on metformin and another antihyperglycemic agent (N=229) and patients not on any antihyperglycemic agents (off therapy for at least 8 weeks, N=41) were randomized after a run-in period of approximately 10 weeks on metformin (at a dose of at least 1500 mg per day) in monotherapy