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Expanding safety assessments to additional animal species, including non-human primates, will be crucial for determining the feasibility of clinical translation

A dose increase of 2.4 mg once a week was given to participants every four weeks during clinical trials

The catch is that your appetite-regulating hormones (leptin, ghrelin, PYY) remain dysregulated for 12-24 months, making weight regain likely through increased hunger and reduced satiety
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