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In the past seven years, the proportion of new, commercial patients who are rejected for a launch brand increased from 37% to 56%, such that more than half of the attempts to initiate a new treatment in 2022 were unfilled the first year

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Subsequently, pharmacologic agonism of GLP-2 has gathered interest for the treatment of patients with conditions pertaining to the loss of intestinal anatomical and/or functional integrity to a degree requiring parenteral support, collectively referred to as intestinal failure

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