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Most people taking semaglutide begin noticing appetite changes within the first two weeks, with measurable weight loss typically appearing between four and eight weeks of consistent treatment

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Diet-induced weight loss (WL) leads to increased hunger and reduced fullness feelings, increased ghrelin and reduced satiety peptides concentration (glucagon-like peptide-1 (GLP-1), cholecystokinin (CCK) and peptide YY (PYY))

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