gip and glp-1 agonist Receptor Agonism Attenuates Receptor Induced Nausea Emesis in Preclinical Models — Hayes Lab New strategies for the treatment

GLP-1s show great results but work best for weight management as part of a comprehensive program that combines a nutritious diet, appropriate levels of exercise, healthy amounts of sleep, and stress management

This spring, on an earnings call with Pepsi, the daughter of an analystwho was with her dad for Bring Your Kid to Work Dayhad one question for the CEO of the beverage giant: So what do you think about the launch of GLP-1 oral medications coming to market next year? If only the Gila monster could talk

A gastrointestinal (GI) hormone, GLP-1, and a gastric inhibitory peptide, GIP, are secreted in response to food consumption

This results in increased stimulation of anorexigenic POMC/CART neurones and decreased activity of orexigenic NPY/AgRP neurones, profoundly altering appetite signals (Trapp and Brierley 2022)

Additionally, they reduce oxidative stress and promote nitric oxide synthesis in endothelial cells, improving vascular health