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This combination can strain kidney compensation mechanisms, particularly in patients with pre-existing renal impairment

The current guidance is based on data from OMMs that have shorter titration windows and achieve lower mean treatment responses

Increase physical activity

However, this should be approached cautiously and under medical supervision to avoid rapid weight regain

Look for products that provide at least 200-400 mg of sodium, 200-400 mg of potassium, and 60-120 mg of magnesium per serving
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