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The Effect of Adiponectin in the Pathogenesis of Non-Alcoholic Fatty Liver Disease (NAFLD) and the Potential Role of Polyphenols in the Modulation of Adiponectin Signaling

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Tirzepatide has two non-coded amino acid residues at positions 2 and 13 (Aib, -aminoisobutyric acid), and is acylated on K20 P (P indicates that the residue belongs to the peptide) with a Glu-2OEG linker and C18 fatty diacid moiety

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Farnesoid X receptor responds to bile acids and represses cholesterol 7alpha-hydroxylase gene (CYP7A1) transcription

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