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Verma S, McGuire DK, Bain SC, Bhatt DL, Leiter LA, Mazer CD et al (2020) Effects of glucagon-like peptide-1 receptor agonists liraglutide and semaglutide on cardiovascular and renal outcomes across body mass index categories in type 2 diabetes: results of the LEADER and SUSTAIN 6 trials

Patients with obesity-related heart failure, particularly HFpEF, who experience symptoms like breathlessness and reduced exercise capacity, may also benefit as emerging evidence suggests these therapies can improve symptoms and quality of life.Who should avoid them or exercise caution before use

Studies of endogenous GLP-1 release and administration of long acting GLP-1 agonists show two mechanisms of action (78)

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