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These medications work by mimicking a hormone that targets areas of the brain that regulate appetite and food intake

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( Figure 1 ) It is also important to highlight the complex neuronal architecture of the tongue, as we should consider three different innervation types: 1) Autonomic innervation: generates the salivatory stimuli and regulation of local blood flow, that plays an important role in food pleasure and avoidance (26) 2) Motor innervation: control of muscle movement, such as mastication, swallow, speech, and breathing (27), and 3) Somatosensorial innervation: that encompasses taste perception, nociception and proprioception (18)

J., Pharmacokinetics of Dipeptidylpeptidase4 Inhibitors, Diabetes, Obesity and Metabolism 12, no

Topiramate (sold under the brand name Topamax) is an anticonvulsant medication